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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '108574effd541642e2997be8df1b60011a6368cf4241d54316a6e096c144093f' 
  AND token = 'XmWmexmlXxMflWN3LCLtwp5fmXN3vid1e2DvXEalh/U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}