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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0bb2f7a1b810f850f8acb9127c7fe63815fc5bb456b77b93f448bfb76d1f7deb' 
  AND token = 'Qeifvk0nPgYyuy47K10DkcljI2I68uks0ioEjM2oQmQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}