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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f4e215dcfef934db5bfb421a304c22443301d6bbbd7b3b862486c56145f266e9' 
  AND token = 'mdx6d3BHCMd3t2m5y2UUXDZL+yp4tmoiOSNDOGrck8E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}