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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e0594edaca012508092e551a7337f09a89750c7831fb4c7e22b3b5eaba0deb6c' 
  AND token = 'jUyK0KhJ13mFyc81T44j5Wu+L9XrRNbpWp9z4UUzMcE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}