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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '23ff7b0596ae3034caf54c74374ac509613d56f28fc1c9654e1d6d31fd61f574' 
  AND token = 'CrXWLe1N+DO4xdItj8vyUrF5K9N4cMBZWtenoWCUJD8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}