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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4326b4597555dca2fa4151655f3307ee5d3783a67b431f0225b664426004afde' 
  AND token = 'F035UluRTF58nYB0Yjn4UZYBQnFPuojHuf4p5iMFhEM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}