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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d005c19996bd73a0fa6f66de0c255e61844fd39e84242f4740e79871fc5487c' 
  AND token = 'JJHjBQoid73lzURZLz7mckhKckg3TE38CmQsi7V4M6I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}