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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b88251883add8682ba0cdd48df5450b4f2e844acd933fa30ce39bed5fbad446' 
  AND token = 'PfSK32d1WCGKc6vGbZ19LXhJDnA0FdPWK3acyTnfhzc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}