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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cf24c57cedb277daac68b96e645055a19094d34d865ae20e85fc45746cabe8a5' 
  AND token = 'nO1Y7/VshMevwN3pAYKOK+srhAlUvJpoJDO0yi94t9E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00078

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}