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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ccb2f1c6a5bf891849151267dca61f0052e9a30f0c9a0a83a8cee24330c12a4' 
  AND token = 'LZw0Dv598HQj3a76wWJ3MQz3jqX2IH8vO6wtVwOBL8Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}