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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22f842549739859b0f1a32492f3418d883b5b41f6d6c5a278af30ddafe55e1f0' 
  AND token = 'PkbqFmn4V+85H8eJ1rAOfanVMxQcE9dnoUHCTR40frI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}