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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d23d7c8a50c370fcc2b2d7351b30bbfd64fa53a9c41a7c10d477e03a9e0b065' 
  AND token = 'S5VrB/pX4BG6BUonTcDiDFZYBAWtai9oqU2bEx1BIz8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}