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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e99e868ec43728f72bef7e3dd2b1f82f3b7a9035e432bf4d77b89a9a9248426' 
  AND token = 'NB8E9WIFo354uUCkmr2P1N2rS+bGY/cPDwc56+aDU64=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00062

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}