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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b5a25bac18e4c3669ff8b1e776430e48ebb4293a99f14d9fb3c856f46b562073' 
  AND token = 'y6DIP+/VKsM7uo43/SUa8uE9UaT1RBNhgioD2N8tWTo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}