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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1243224ddca6bfc33ce454c7c7dbec9b2cf030dca1e47ea7caaf624562d9f96b' 
  AND token = '3I8fCXQ4DDrOTfzHebIS4XLCJ4K/PVWarwH+kfv4rQE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}