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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '195a324392a9bf2647f5a3d3bc5e364b7c4c84ee9bfe46e1abc9608a4bd75944' 
  AND token = '1VrhAVkcdb9RiEaDgXBxvH8/HJfaMOn5fSM0+IbVS8A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}