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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '149b6190fe44f50d6092d81bc088da8f95535e1b90ccb86493b03f43d9436978' 
  AND token = 'TIy0r/BqIBJVJXGnYfxh8RHUN6DISNUrnOD1iQ3mixc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}