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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '963c20f0c6bf922d2b641a18858e255399b9500aca718484d22da601af15957a' 
  AND token = 'wU2CFge2Y7NP9dVDPoStiqd9We1fhQMQvAcJ0tjZ0nc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}