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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f7b7d2b614d336468106bf416a4af21c00a1deeea7497f28b98cb82fb89b04f' 
  AND token = 'e53rLZL68NNcHRt72aAdhDyg1vGewe9JxOiaxDhtMVQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}