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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b1d9c79d0955880dbc6f8801c34bef05669171eae556f1e4202b94c84595901' 
  AND token = 'JBcWYg2Pk92qFjj5/KmPjoe/kUN2JHEzjgJVcjnj8z0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}