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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f25e7f09cfdac19e70d04e2193d04270cfe9510a49825a241458467209f2cb10' 
  AND token = 'RWLyE49+bnD8T2N8lDJuRvZdLbn5sPz+4AM4mN8eXcc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}