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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '27d002936672587418dd77c866711f942af7500c902545ce3256ec959992f6df' 
  AND token = 'vZSMA0AiyTf4G1Pt1RT3OaJL4rP688/155uvzfV9Kzc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}