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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33e3427aa978490fb8823ff0259376a9f5d71b416286ffd68af58145824dbcc8' 
  AND token = 'j3dZmEF+0bD0BNfxG7N+xuGoGFHOsEEt0YxCCG9Nl5Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}