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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a1cb0da5d632f6814a86a47f2b5ee6e275790e2d27b61c1e7c02bf6ee7041412' 
  AND token = 'V7bWkizOMGpEM+buVkachiqyGAnM5R2q+dXhw96efik=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}