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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e7e0298de808fed430cddf5841e940b8b8b3f1a0f2081e342b2068468a329a8' 
  AND token = 'Se5E2lOGoM9KdcOYt2sPwt+rCR7/I5Kf4OWvuiXL+x8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00077

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}