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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a28fcbcc6fcda3807ac272e38280ccb627b362db61c7f64daf67ea085dd91c6' 
  AND token = 'AzFXZAzH1G46U1mNsZgMoW1uHSeyb9AUW+3TC+TwigM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}