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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '150108c253a582e43fa627a5e234beebafa3bc40996590f574ffe6b762089ba2' 
  AND token = 'RtsEx4twkd4tcN9/MF+o8PPex2mDOqF+cblPfR/bKJI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}