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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '119a88a2c358e64c05aba4eb611083cb28f29634df2de3475a428b4485a01a9f' 
  AND token = 'crXvZwA2DL1FFnpLlSWbSJKlFvtVET9KqFzzV3kUAyM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}