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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53d8f0c873735612a514b1109146d69bbc3852905b2bcb8ae56c139fbbf00fc7' 
  AND token = 'PRqQsGRdssb5LdpVHLTTTYIXlPAZ0KR6llSWfd48eoQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}