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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8bcdd98fd26bf4ef05925c62f20eda89c061d3ebdd7e78448945048ad435c25' 
  AND token = 'J0JXwW9MhNJNiOYVZLV1joIaOcdydC8qZ0byVkTDXDM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}