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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af68cb61e84d6ed24581e814767e21593a028126b9b083e1b0a2b9e222586f55' 
  AND token = 'jm2lRTXzTADHE+QDrH8SPdGk8gGvwjoOiEHpaGWNcuQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}