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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fc9b0acf73e1865cb6742a024e7e5485fe85a2b0437612f4bcbc557be3c481c2' 
  AND token = 'Iz2HAh7Q70Zs2AUe8ja0r2qS7ICikC1BEZSL/l7yHxw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}