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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a7c51786de49b1a7e1219cb6715fa680750fe99e7b7030042140bb3ca30ad340' 
  AND token = 'cezOFFGhpPSVgN/Uy4S/YJA3ewpSYUItRzvw1fhSt0I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}