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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ef56b76f4174ccd9cc3081a6e6e5d4f4bbe2bb8440f3c07e6adbfd4fa4918d2' 
  AND token = 'XY50i56/PP0yjGcRMaA3JbJI6jqxD+rMMeGExho9jmM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}