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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c964378003c6adb29ae234c916c69916434bdbff01cb9a0df2dedf951f2160bd' 
  AND token = '9T/IsxeeS45B7QxjVB7xHoWGkO7kWLecN9QCQ+ByYeo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}