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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7327e39f1cdb02fa6237729fabbb037b340e88aac502177e42c0bb03f20cb3db' 
  AND token = 'BMC73maFxpRMM5pai1W5jyMPDf5YsaBvdMSDck3MYQI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}