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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a4ea4c017188e496b044d24f7bce71b5c182d42621f7d25c7a0588d50087bff' 
  AND token = 'LlqXkXc5WGn/xA++CQsZsciktRfVwGwF1DMQ89NTt8E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}