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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48709432adbf6a90d75462f63a17025e0e5a48361cfb649b0b01869a63b7e896' 
  AND token = '1Z1Cn/rxfWABVC93K7raagjAXU5a0Fr8HWLvdT3uS8o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}