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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '28f4656158adc6dd66afbe7d31ea9188bbb45af7eae5e69f548bef1e01591362' 
  AND token = '8jBxp5NsBIUqO2dE7eW+ZmacaKQKUv0ZYieZPNdJgD8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}