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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a218126fc1891b25f6fd51ccb9529e6bb40fdf9e4b9b6863bc4a830770981a9' 
  AND token = 'nw8y7fR0DEb9Pq3n4cUn9WQM9vHl9FQGce5ZLFN0VH0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}