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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a4841f27ab30567276e000092e2bceabfca8cb625b11cdd15fe053a11784089' 
  AND token = '2/VNXoMJMvXkE7/+Kl+1kuAbgjBKfp30GdpuQ+cp8no=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}