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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de6e44e6ae826aa9973887f588cf69072394626d3045c5df7b16ce4e020b6a6e' 
  AND token = '8jFWNdXAcD7ixuiImRMuRcvT3Cvr6HMbc/8HYb157Yw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}