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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e8683ec113ab24d3d83b135ae5395429928386f24b3bc8928803698d1f58f4c' 
  AND token = 't8W9kuUUyvf8dPqHGlH9DcTFPtY4UtzJ395IFdilyso=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}