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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f6b4e6f0083775edb91b888228bacf6a574b36a61657543db581875eb2b7bbff' 
  AND token = 'yNj/YTQvgkPloL4vC/hWIN46bVAYwq9c8XSP98u8Pdc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}