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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1f80fb8807a99fa84e88a6514ba9f9192664adb2e0a7a8043538401c7983b3fc' 
  AND token = 'tttFazqReiPFDxR8KCW5HHkOBW2vNh3HguNSO6v38GY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}