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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59e3f2d14169863b32b09306f4ea433440b2eb7ee092b64c8227b6548c585dbe' 
  AND token = 'BG6r0woa0vh51I0PRmdrA9UnKeD4/bZb03RhRNG9dfQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}