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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '47acaf29d90bc9454c9c05e80ed27292b8f2d5c486755d71ec30c6fa4fb21223' 
  AND token = 'dbHMCtnDwmHXKU9Zj2XmZHjEdA0UKjAl7m10a0hG7wo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}