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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9ff38577393c457d30d2fbf8d90ed70ec75f642b15ae62c8a5a5b4cb10324579' 
  AND token = 'EDefIK5keMfJ7jZJaJyJzHvvBuTXA4AtdToKKOj7+xk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}