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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53265fb2bc16d10286340fa01425e1b2798c8cdfcb37d430811dc22ab8a18076' 
  AND token = 'aly9WXuoXSaslsnjEwMR/FNGjdZ9DEiP3J4DcnBvfjI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}