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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de2e6e75ee8e236cce67ca1c590cc0de737e692263caa0f68dd3afd74a3742ad' 
  AND token = 'XDxhPIGyhwmYpWT6D01R+NEfKLhHvzDxc9ub2lMnv5g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}